Shivani Yadav

Research Associate | Data Analyst

Email: [Email Hidden] | Phone: [Phone Hidden] | LinkedIn: View Profile

Experience

Research Associate: BioGenomics Ltd, Lab of Cell Biology | Sep 2023 – Present

• Extensive experience in Next-Generation Sequencing (NGS), encompassing end-to-end execution of experiments related to cancer and diabetes research.
• Skilled in implementing cutting-edge NGS techniques to investigate genetic mutations, transcriptomic profiles, and epigenetic modifications.
• Directed comprehensive biological characterization of insulin aspart and conducted biosimilarity studies for various insulin types.
• Authored method development reports, qualification reports, and SOPs for validated assays.

Senior Research Associate: Syngene International Ltd, Lab of Cell Engineering | Jul 2022 – Feb 2023

• Worked on Neuroblastoma reporter cell line generation and gene transfer techniques.
• Performed Knock-in via CRISPR and Multi-landing pad DNA integration in mammalian cells.
• Utilized Fluorescence-activated cell sorting (FACS) in research activities.

Data Analyst: Centre for DNA Fingerprinting and Diagnostics, Lab of Molecular Oncology | Feb 2020 – Jun 2022

• Investigated the contribution and interplay of molecular markers in colorectal cancer.
• Conducted Whole Exome Sequencing to identify novel mutations in colorectal cancer samples.

Education

Master of Science in Genetic Engineering: Dr. D. Y. Patil Deemed to be University, Navi Mumbai | 2017 – 2019

Bachelor of Science in Zoology: Bhavan’s College of Science and Arts, Mumbai University, Mumbai | 2014 – 2017

Publications

• (Submitted by Department of Biotechnology, Govt. of India) on Global Initiative on Sharing All Influenza Data (GISAID) database.
• Dissecting the contribution and interplay of MSI and CIMP in colorectal cancer (CRC) in India: The work is currently being compiled for the communication of the manuscript.

Skills

Next Generation Sequencing, Tumor Tissue Handling, Microscopy, Molecular Biology, Protein Biology, Infection Biology, Software/platform

Fellowships/Awards

• University First Rank in II Year Master Degree – Jun 2019
• Selected to participate in funded Tata Institute of Fundamental Research Science camp

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Cover Letter:

I am excited to apply for the Genome Analyst position at Medgenome. I have a strong background in next-generation sequencing (NGS), molecular biology, cell culture, and molecular oncology. Hands-on experience in genome analysis, variant detection, and molecular profiling makes me well-suited for this role.
In my role at CDFD, Hyderabad as a Data Analyst, I have been extensively involved in NGS-based cancer research, performing sample preparation, library construction, sequencing, and downstream variant analysis. My expertise lies in identifying genetic mutations and epigenetic modifications, contributing to biomarker discovery and disease mechanism elucidation. Additionally, my experience in Whole Exome Sequencing (WES) from my tenure at the Centre for DNA Fingerprinting and Diagnostics (CDFD) has strengthened my ability to analyze tumor genomics and hereditary mutations.
My technical proficiency includes working with Illumina sequencing platforms, FastQC, BWA, STAR, and GATK tools for NGS data analysis. With a keen eye for quality control and data interpretation, I ensure accuracy in genomic assessments that drive impactful research. Beyond technical skills, I thrive in collaborative environments, contributing to method development and optimizing protocols for high-throughput sequencing.
I am eager to bring my NGS expertise and analytical skills to your team and contribute to Medgenome’s advancements in genomic research. I look forward to the opportunity to discuss how my experience aligns with your goals.
Thank you for your time and consideration.