Shifa Sheikh – Unleashing the Future of Healthcare Through Groundbreaking Biotechnology Research

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SHIFA SHEIKH

Location: Hyderabad, Telangana, India

Summary:

Motivated postgraduate in Biotechnology with a strong foundation in molecular biology and computational tools. Seeking an entry-level R&D position to apply and expand knowledge through hands-on laboratory research, while contributing to innovation in healthcare and therapeutic development.

Education:

Masters of science in Biotechnology
Osmania University, Hyderabad, Hyderabad, Telangana, 2024

Bachelor of Science in Biotechnology, Biochemistry and Chemistry
Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra, 2022

Higher Secondary School Certificate
Rajiv Gandhi Mahavidyalaya, Chandrapur, Chandrapur, Maharashtra, 2019

Secondary School Certificate
Stella Maris Convent High School, Rajura, Chandrapur, Maharashtra, 2017

Skills:

  • Molecular Biology Technique: PCR, gel electrophoresis, SDS-PAGE, DNA/RNA extraction and purification, Sanger Sequencing
  • Microbial Techniques: Isolation of micro-organism, Serial Dilution, pH meter calibration, Autoclave, antibiotic susceptibility testing
  • Computational Tools: Molecular Docking (AutoDock, PyRx, and SYBL), Genomics Data Handling (BLAST, Clustal Omega, and PubChem), Protein Structure Analysis (SWISS-MODEL), Biological Databases (PDB, NCBI)
  • Microsoft Office: Word, Excel, Powerpoint

Achievements:

  • GATE-2025 Qualified, Score: 29
  • Successfully completed a molecular docking project involving kinase proteins and alkaloids
  • Participated in various workshops to enhance laboratory and bioinformatics skills

Certifications:

  • Forensic Science Basics – Dr. Ambedkar College, Department of Biotechnology and Biochemistry, 2021
  • Cancer Biology – II.Sc Bangalore, 2023
  • CRISPR-Cas9 Workshop – Precision Gene Editing, Biotecnika, 2023
  • Gene Wise Workshop – PCR, NGS & Sanger Sequencing, Genome Foundation, 2025

Projects:

Title: In-Silico Docking Analysis of Alkaloids on Kinase Mutants Linked to Hematological Malignancies
Duration: November 2023 – August 2024
Supervisor: Dr. Rama Krishna Kancha (Director of CPMB, Osmania University)

  • Independently conducted molecular docking studies on tyrosine kinase mutants (ABL, c-KIT, FLT3, PDGFRA), evaluating alkaloid binding interactions for therapeutic potential.
  • Investigated binding affinities and structural interactions of alkaloids with these kinase mutants to identify potential therapeutic candidates.
  • Utilized AutoDock, PyMOL, Chimera, and Discovery Studio for molecular docking, visualization, and interaction analysis.
  • Identified key binding affinities and structural interactions, contributing to the understanding of kinase inhibition mechanisms.
  • Contributed to data analysis and optimizing docking protocols for accurate structure-function predictions.

Professional Affiliation:

  • Member, Indian Science Congress, Kolkata
  • Member, Seeding Labs, DACN, Maharashtra

Languages: English (fluent)

Skills:

Molecular Biology, PCR, gel electrophoresis, SDS-PAGE, DNA/RNA extraction, Sanger Sequencing, Microbial Techniques, Isolation of micro-organism, Serial Dilution, pH meter calibration, Autoclave, antibiotic susceptibility testing, Computational Tools, Molecular Docking, Genomics Data Handling, Protein Structure Analysis, Biological Databases, Microsoft Office

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Cover Letter:

Subject: Application for QC Internship – Biotechnology Fresher

Respected Sir/Madam,

I am writing to express my interest in the QC Internship position for freshers at Oracity Life Sciences. I have completed my MSc in Biotechnology from Osmania University, Hyderabad. I possess practical experience in core molecular biology techniques such as PCR, gel electrophoresis, and microbial isolation. In addition, I am familiar with protein modeling and molecular docking using various bioinformatics tools.

As part of my Master’s thesis at the Centre for Plant Molecular Biology (CPMB), Hyderabad, I conducted a project involving molecular docking targeting protein tyrosine kinase relevant to hematological malignancies. This experience enhanced my analytical and documentation skills, which I am eager to apply in a GMP-regulated QC environment.

I am enthusiastic about the opportunity to contribute to Oracity’s commitment to quality and innovation. I have attached my CV for your kind consideration and would welcome the chance to discuss my suitability for the internship.

Thank you for your time and consideration.

Yours sincerely,
Shifa Sheikh

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