Ipsita Panigrahi – Unlocking the Secrets of Schizophrenia: A Rising Star in Biochemistry

IPSITA PANIGRAHI (She/Her/Hers)

Email: [hidden] | LinkedIn: [Link]

Work Experience

NIMHANS – Neurobiology Research Centre- Bangalore, Karnataka

Mar – Sep 2024

Postgraduate Research Intern (On-site)

• The thesis study focused on studying the transcription regulation of Kynurenine pathway metabolites and pro-inflammatory cytokines as factors responsible for the onset of schizophrenia using post-mortem brain samples involving the primary molecular screening technique qRT-PCR. Protein expression analysis of the respective gene was performed using Western blotting.
• Analysis was done using R software and ggplot to compare the fold change of the gene of interest between healthy control and schizophrenia post-mortem samples.

MEDIOMIX DIAGNOSIS AND BIORESEARCH – Bangalore, Karnataka

Sep – Oct 2023

Advanced transcriptomics Intern (On-site)

• RNA-sequencing analysis of Cervical cancer dataset (SRR_ID: SRR12708071) to analyze the role of HIF-1α as a genetic hallmark of cervical cancer.
• Analysis of the dataset using various Linux-based tools to quantify gene expression and generate a list of differentially expressed transcripts between control and condition.
• Plots generated using R was used to demonstrate differentially expressed genes.

Education

JSS ACADEMY OF HIGHER EDUCATION AND RESEARCH, Mysuru, Karnataka (School of Life Sciences)

Nov 2022 – July 2024

Master’s of Science – Biochemistry

• CGPA: [hidden]
• Core Modules: Biochemistry, Molecular Biology, Plant Biochemistry, Immunology, Techniques in Biology, Cell Biology, Clinical Biochemistry, Biostatistics, Genomics & Proteomics
• Research Project: Research Intern at Dr, K Gokulakrishnan’s lab, Department of Neurochemistry (6 months) in NIMHANS, Bangalore.
  Thesis title – “Transcription Regulation of Kynurenine Pathway Metabolites and pro-Inflammatory Cytokines in postmortem Schizophrenic Brain Samples”

JYOTI NIVAS COLLEGE AUTONOMOUS, Bangalore, Karnataka

June 2019 – May2022

Bachelor’s of Science – Biotechnology, Biochemistry, Genetics (Triple Major)

• GPA: [hidden]
• Core Modules: Molecular Biology, Biochemistry, Genetics, Immunology, Microbiology, Biotechnology & Bioprocessing, Bioinformatics, Chemistry, Human Anatomy & Physiology, Biostatistics
• Research Project: Research Intern at Jyoti Nivas College, Department of Genetics under the guidance of Dr Reema Orison Lobo.
  Thesis title – “Evaluation of toxicity by Argemone Mexicana on subcutaneous administration into freshwater fish Danio Rerio”

Publications

Novel Drug Targets for Small Molecule-based Drug Discovery – Book Chapter…Nov 2024

Certifications

Coursera:

1. Introduction to Forensic Science – Nanyang Technological University
2. Introduction to Biology of Cancer – John Hopkins University
3. Science of Exercise – University of Colorado
4. Clinical Research – Leads
5. Medical Lab Technology – Azyme Biosciences
6. Nutrition and Dietetics

Other Certifications and Workshops:

• Workshop on basic and advanced transcriptomics – Mediomix Diagnosis Bioresearch
• Python for genomics – BDG Lifesciences

Skills

DRY LAB:

• Programming Language: R, Python for genomics, Shell-scripting, Basics of Linux
• NCBI-Primer Blast
• TECAN
• ImageLab
• GraphPad Prism

WET LAB:

• Analytical Instruments:
  • Liquid Chromatography-Mass Spectrometry
  • Spectrophotometer
• Histology: Identification of micronuclei using H&E staining
• Molecular Biology:
  • Gel electrophoresis
  • Nucleic Acid Isolation from human samples
  • Protein Isolation and Purification
  • Protein quantification
  • Real-Time PCR
  • Reverse Transcriptase PCR
  • Western Blotting
• Danio rerio maintenance

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Cover Letter:

**Dear Hiring Team,**
I am excited to apply for the **Genome Analyst** position at **MedGenome**. With a postgraduate degree in **Biochemistry** from JSS Academy of Higher Education and Research, I have always been fascinated by the intersection of molecular biology and data science. My journey into computational biology began with sheer curiosity, but it quickly turned into a passion that I am eager to build my career around.
Though my academic background is in biochemistry, I proactively sought opportunities to develop bioinformatics skills. I participated in an **intensive workshop and internship on basic and advanced transcriptomics** at **Mediomix, Bengaluru**, where I gained hands-on experience in **Linux and RNA-Seq data analysis**. Wanting to deepen my computational knowledge, I also completed an online course on **Python for Genomics** by BDG Lifesciences. These experiences have not only equipped me with essential skills in NGS data analysis but also strengthened my problem-solving abilities in this evolving field.
What excites me most about this role is the opportunity to work on **real-world genomic data**, contributing to research that has tangible impacts on healthcare. I thrive in environments where I can **learn, adapt, and grow**, and I am eager to bring my analytical mindset and dedication to your team.
I have attached my resume for your review and would love the opportunity to discuss how my skills align with this role. Thank you for your time and consideration—I look forward to hearing from you.
**Best Regards,**
**Ipsita Panigrahi**