Chetan Chavan – Unlocking the Secrets of Life: A Bioinformatics Pro on the Cutting Edge of Science

Chetan Chavan

Aurangabad, Maharashtra

Summary

Bioinformatics student with a strong foundation in computational analysis and a comprehensive understanding of Bioinformatics tools. Proficient in utilizing diverse methodologies to derive valuable insights from complex biological data. Seeking to apply advanced computational skills to innovate and address pressing challenges in the realm of biology and computational biology.

Education

• Bachelors- [hidden] Bioinformatics
  MGM Institute of Bioscience and Technology, Aurangabad, Maharashtra
• Masters- [hidden] Bioinformatics
  Amrita School of Biotechnology, Kollam, Kerala

Professional Experience

• Summer Intern
  Coding Vision, Aurangabad, Maharashtra
• Project Intern for Dissertation
  Zoological Survey of India, Gopalpur, Odisha
• SERB Project JRF
  Osmania University, Hyderabad, Telangana

Projects

• Developing 3D Structure of Annexing of Aspergillus
  More proteins are being discovered than we can understand their shapes. This makes it tough to design drugs based on their structures quickly. To fix this, we need to use a method called homology modeling in structural bioinformatics. It helps us predict what these protein shapes might look like even if we haven’t found them yet.
• Analysis of transcriptomes involved in Aedes albopictus diapause mechanism
  To identify differentially expressed genes (DEGs) associated with Aedes albopictus diapause mechanism and its termination with exposure to pyriproxyfen
• Prognostic and immunological effects of SPP1 mediated crosstalk between malignant cells and Tumor-Associated Macrophages (TAMs)
  and its role in Chemo-Resistance in Cervical Cancer

Skills

• Bioinformatic Tools and Databases: BLAST, Swiss Model, NCBI, PDB, Galaxy, CLUSTAL-W, MEGA, Bioedit, PDBsum, Pymol, Docking(Autodock), Mysql, Linux, Programming WordPress
• Programming Languages: Python, C Programming, R Programming, JAVA (Basics)
• Entomological and Specimen Handling: Trap installation, specimen pinning, larva collection, species identification, molecular DNA barcoding
• NGS (Sequence Analysis): Galaxy software, Linux Terminal, GEO Dataset, String
• Molecular Techniques: DNA, Protein extraction, Western blot, SDS PAGE, BCA assay, RIPA buffer, agarose gel electrophoresis, protein estimation
• Cell Culture: Sterilization (fumigation, autoclaving, UV, alcohol), Cell culture (revival, freezing, passaging, treatment), inverted microscopy, Bacterial transformation, Competent cell preparation

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Cover Letter:

Chetan Chavan
Aurangabad,
Maharashtra 431001
[Phone Hidden]
12/02/2025
Hiring Manager
MedGenome Labs Ltd.
Bengaluru, India
Subject: Application for the Position of Genome Analyst
Dear Hiring Manager,
I am excited to apply for the Genome Analyst position at MedGenome Labs Ltd. With a strong background in bioinformatics and hands-on experience in Next Generation Sequencing (NGS) data analysis, I am eager to contribute to your esteemed organization’s cutting-edge genomic research and diagnostic advancements.
I have completed my Master’s in **Bioinformatics **from Amrita University, equipping me with a solid foundation in computational biology, genomics, and data analysis. Currently, I am working as a Junior Research Fellow (JRF) at Osmania University Hyderabad, where I am involved in a DST-SERB project focusing on the prognostic and immunological effects of SPP1-mediated crosstalk between malignant cells and Tumor-Associated Macrophages (TAMs) in cervical cancer. My experience includes working with NGS data, performing quality control checks, analyzing sequenced variants (NGS/Sanger sequencing), and interpreting genomic results. Additionally, I have collaborated with bioinformatics and laboratory teams to ensure accurate analysis and reporting of genetic data.
My skills align well with the requirements of this role:
– Proficiency in NGS data analysis, human genetics, and genome sequencing.
– Experience in quality control of NGS and other genetic datasets.
– Strong ability to interpret sequencing results and generate comprehensive reports.
– Effective communication and collaboration with cross-functional teams.
– Participation in internal research projects and molecular biology activities.
I welcome the opportunity to discuss how my expertise aligns with the needs of MedGenome Labs Ltd. Thank you for your time and consideration. I look forward to the possibility of contributing to your innovative research and diagnostic efforts.
Sincerely,
Chetan Chavan