Amulya Rao T – The Bioinformatics Powerhouse Transforming Drug Discovery with Next-Gen Tech

Professional Summary:

Driven and detail-oriented bioinformatics student with dual MS degrees in Biotechnology and Cellular & Molecular Medicine. Specialized in utilizing bioinformatics tools and next-generation sequencing (NGS) workflows for data analysis in drug discovery and personalized medicine. Proficient in bioinformatics software like MEGA, Pyrx, and Swiss ADME, with complementary knowledge of molecular biology techniques and pharmacokinetics. Passionate about applying big data analysis to advance clinical trials and therapeutic innovations.

Skills:

• Bioinformatics Tools: NGS pipelines, Pyrx, Swiss ADME, ProTox, MEGA, EMBOSS Needle and EMBOSS Water, BLAST, Molecular Docking, Microarray using GEO2R
• Programming & Data Analysis: Proficient in Python, R and GraphPad Prism
• Molecular Biology Techniques: PCR, DNA/RNA extraction, gel electrophoresis, ELISA
• Lab Equipment: Spectrophotometer, Centrifuge, pH meter, Laminar Air Flow
• Software Proficiency: MS Office Suite (Word, Excel, PowerPoint)
• Languages: English, Hindi, Kannada, Telugu

Professional Experience:

Bioinformatics Intern- Bionome
Sep 2024 – Present

• Developed phylogenetic trees using MEGA to analyze evolutionary relationships, improving interpretation of bioinformatics data.
• Utilized Swiss ADME and ProTox to predict pharmacokinetics and toxicity profiles for bioactive compounds.
• Conducted molecular docking for 15 protein-ligand pairs using Pyrx, identifying 2 high-potential drug candidates.
• Understanding and optimizing NGS workflows, achieving an improvement in data processing accuracy with conda environment.

Research Intern – Vipragen Biosciences (DMPK and Discovery Department)
Jan 2024 – May 2024

• Analyzed pharmacokinetic data with Phoenix WinNonlin, generating key insights into drug efficacy and absorption profiles.
• Conducted syngeneic tumor model studies and anti-inflammatory research, contributing to drug development insights.
• Collaborated on rodent behavioral studies, developing and understanding methodologies for more precise results in preclinical trials.

Projects:

Assessment of acute inflammatory model and syngeneic tumor model using rodents
MSc Dissertation Project, Vipragen Biosciences

• Evaluated anti-inflammatory effects of dexamethasone using carrageenan-induced paw edema models.
• Investigated tumor progression and therapeutic interventions in rodent models, contributing to oncology research.

Education:

• MSc in Biotechnology, Amrita Vishwa Vidyapeetham: 2022 – 2024 | CGPA: [hidden]
• MS in Cellular and Molecular Medicine, The University of Arizona: 2022 – 2024 | GPA: [hidden]
• BSc in Chemistry, Microbiology, Biotechnology, Jain University: 2019 – 2022 | CGPA: [hidden]

Certifications & Workshops:

• Certifications
  • Drug Discovery and Industrial Biotechnology | Coursera
  • Introduction to Clinical Research | Udemy
• Workshops
  • Primer Designing | NextGen Life Sciences
  • Designed primers using Primer3plus and web-based tools.

Keywords: Bioinformatics Tools, NGS, Python, R, Molecular Biology, Data Analysis, PCR, Drug Discovery, Molecular Docking

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Cover Letter:

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