Abhishek Ghutke – Unlocking the Secrets of Drug Discovery Through Bioinformatics Mastery

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Abhishek Ghutke

SUMMARY

I have an MSc in Bioinformatics and look forward to opportunities in Drug Discovery, NGS, and multi-omics analysis. I am passionate about contributing to healthcare advancements through the development of cutting-edge computational biology tools, leveraging multi-omics, artificial intelligence, and machine learning techniques.

WORK EXPERIENCE

Project Intern at IIT Delhi

  • Next Generation Sequencing data analysis of ESKAPE pathogens support genomic research and antimicrobial resistance studies
  • Dec 2024 – Present

EDUCATION

Master of Science in Bioinformatics

  • Dr. D Y Patil School of Biotechnology and Bioinformatics, Navi Mumbai 400614
  • CGPA: [hidden] / 10

Bachelor of Pharmacy

  • Smt. Kashibai Navale College of Pharmacy, Pune kondhwa 411048
  • CGPA: [hidden]
  • July 2019 – June 2023

PROJECT

Bachelor’s Thesis

  • In silico design and synthesis of some heterocyclic compound as antidiabetic agent
  • Associated with Sinhgad Technical Education Society’s Smt. Kashibai Navale College of Pharmacy, Kondhwa bk., Dist. Pune 411048
  • Jan 2023 – June 2023

TECHNICAL SKILLS

  • Computer Coding skills: Perl Programming, Python and Bio-python, C Programming, Microsoft (Word, Excel, PowerPoint)
  • Bioinformatics Databases: NCBI, PubChem, Ensembl, UniProt, STRING, PDB, GEO
  • Alignment Tools: BLAST and BLAST Variants, Jalview, Clustal Omega, T-Coffee, WebLogo
  • Phylogenetic Analysis Software: MEGA, Phylip
  • Protein Docking Tools: AutoDock, AutoDock Vina
  • Structure Visualizer: Chimera, Discovery Studio, Swiss-Pdb Viewer
  • Interaction Analysis: Cytoscape, String Analysis
  • MD (molecular dynamics) simulation GROMACS

REFEREES

Dr. Pramodkumar Gupta

  • Associate Professor, DY Patil School of Biotechnology and Bioinformatics, Navi Mumbai
  • Email: [hidden]
  • Mobile no: [hidden]

Dr. Selvaakuar C.

  • Associate Professor, DY Patil School of Biotechnology and Bioinformatics, Navi Mumbai
  • Email: [hidden]
  • Mobile no: [hidden]

CONFERENCE ATTENDED

  • Participation at Bioinformatics Conference conducted by Bioclues at VIT Vellore

HANDS ON TRAINING

  • Training in Drug Synthesis at MET Bhujbal Knowledge City, Nashik under the guidance of Dr. Santosh Chajjed Sir (3 June 2024 to 20 June 2024)
  • Conducted the synthesis of Chalcone
  • Acquired hands-on experience with Thin Layer Chromatography, Purification, and Recrystallization technique (3 June 2024 to 20 June 2024)
  • Completed comprehensive training at Bayer Biotech Research Center, Bangalore, in July 2024 focusing on R-programming, advanced plotting techniques, and data cleaning. Gained practical experience in writing efficient R code, utilizing R libraries for data visualization, and preprocessing large datasets for biotech research projects.

LANGUAGE KNOWN

  • Marathi – Native
  • English
  • Hindi – Native

DECLARATION

I hereby declare that the above information is correct and best to my knowledge.

KEYWORDS

Next Generation Sequencing, Bioinformatics, Drug Discovery, NGS, Multi-omics Analysis, Computational Biology, Artificial Intelligence, Machine Learning, Perl Programming, Python, Bioinformatics Databases, Alignment Tools, Phylogenetic Analysis Software, Protein Docking Tools, Structure Visualizer, Interaction Analysis, MD Simulation.

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Cover Letter:

Respected Hiring Manager
I am writing to express my interest in the genome analyst at your company. With a Master’s degree in Bioinformatics and hands-on experience in Next-Generation Sequencing (NGS) and antimicrobial resistance (AMR) analysis, I am eager to contribute my expertise in computational biology and genomics to your [hidden] my academic and research projects, I have worked extensively with NGS data, performing quality control, read trimming, genome assembly, and variant analysis using tools such as FastQC, MultiQC, Trimmomatic. My recent work focused on identifying novel AMR genes in bacterial genomes, utilizing bioinformatics pipelines to analyze large-scale sequencing datasets in a high-performance computing (HPC) environment. Additionally, I have experience in metadata retrieval from SRA NCBI, further strengthening my ability to manage and interpret genomic datasets.
I am particularly excited about this opportunity because it aligns with my goal of becoming an NGS specialist. thank you

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