Premika Priyadharshan – Unlocking the Secrets of Genomics: A Journey Through Science and Innovation

Premika Priyadharshan

Objective

Aim to be placed in a challenging organization that gives me scope to update my knowledge & skills in accordance with the latest trends and be a part of a team that dynamically works towards growth of organization thereof.

Professional Experience

Scientific Curator,

Genomatics Pvt Ltd — Coimbatore. (Jan 2019-Oct 2019, Apr 2020-Jul 2021)

• Worked under the area of pharmacogenomics to curate various disease data like cancer, diabetes and some psychological disorders like Schizophrenia to databases.
• Curated phenotypic and genotypic profiles of diseases and annotated them.
• Described the biological effects of genomic variants and its association with disease using Ontologies and controlled Vocabularies.
• Evaluated the pathogenicity of a variants in genes associated with Mendelian diseases using ACMG guidelines.
• Use of databases like NCBI, Disease Ontology, Mesh on demand, Cosmic, VEP, PharmGKB.

Education

• Master of Science, Biotechnology – University of Madras 2016-2018 | Chennai, Tamil Nadu
• Bachelor of Science, Biochemistry & Biotechnology – Avinashilingam University 2013 – 2016 | Coimbatore, Tamil Nadu

Language Proficiency

• German – A1 certification

Laboratory Experience

• Basic microbiological practices
• Isolation and characterization of microbes from various sources
• Preparation and sterilization of culture media
• Quantitative analysis of carbohydrates, proteins, nucleic acids
• PCR
• ELTSA
• Southern blot
• Thin layer chromatography
• Column chromatography
• Isolation of genomic DNA from Bacteria and whole human blood
• Isolation of plasmid DNA from Bacteria
• Isolation of RNA from plants
• Restriction Digestion and ligation of isolated DNA
• Transformation and selection of rDNA moleculescDNA synthesis, DNA Elution
• Immunoelectrophoresis
• Immunodiffusion
• Agarose gel electrophoresis
• SDS — PAGE
• Semen Analysis
• Primer design
• IUI

Training and Certification

• Certificate Course: Certificate course in Bioinformatics, Department of Biochemistry, Biotechnology & Bioinformatics, Avinashilingam University, 2014-2015.
• Underwent training on “Molecular Biology and Biotechnological Tools for Crop Improvement — ICAR- Sugarcane Breeding Institute, under Dr. K. Lakshmi, Scientist, Division of Crop Improvement during the summer of 2017.
• Master’s Dissertation (Research): A project at KMCH — Kovai Medical Center and Hospital, under Dr. C.V. Kannaki Uthraraj. The topic of my work was “Sperm DNA fragmentation in IUI Failures using Sperm Chromatin Dispersion Assay” during the summer of 2018.
• Software: MMC sperm, RasMol, Primer 3

Extra-Curricular Activities

• Attended NSS Special Camp of one week on the theme Environment including Preservation of Natural Resources and Conservation of Cultural/Historical Heritage’, Avinashilingam University, Coimbatore.
• Participated in creating awareness and assisting in raising funds for the care of the elderly, irrespective of race, religion, caste or creed, Help Age India, Chennai.
• Participated in resource mobilization for humanitarian causes, INDIAN DEVELOPMENT FOUNDATION, Chennai.
• Participated in the seven days NSS Special Camping Programme on the theme ‘Healthy Youth for Healthy India’ organized at Kottur, University of Madras, Chennai.
• Participated as Road Safety Patrol Cadet for the year 2011-2012.
• Participated in the one-day training programme on ‘Motivation of Youth for Inspiring Rural Reconstruction’ on March 4, 2014, organized by the NSS unit, Avinashilingam University, Coimbatore.

Skills

Keywords: Pharmacogenomics, Genomic Variants, Genotyping, Disease Data Curation, Bioinformatics, Laboratory Techniques, Language Proficiency, Cultural Activities.

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Cover Letter:

I have worked as a scientific curator for 2 years where we need good communication skills along with knowledge in science discipline and medical writing skills as well. I hope I can fit into this job role.