**Medha Gupta**
Medical Biotechnologist
**Summary:**
Dedicated and detail-oriented Medical Biotechnologist with hands-on experience in molecular biology, cell culture, protein biochemistry, and microbiology. Passionate about translational research in infectious diseases, drug discovery, and clinical diagnostics. Proven ability to design and execute experiments, analyze data, and contribute to innovative research.
**EDUCATION**
MSc. Medical Biotechnology
Bharati Vidyapeeth, Pune
07/2021 – 05/2023
CGPA: 9.3
Thesis: Determining GAP activity of TBC domain-containing protein against small G-proteins
BSc. Medical Biotechnology
Amity University, Noida
06/2018 – 05/2021
CGPA: 8.71
Thesis: Prevalence of etiological organisms in Urinary Tract Infections and its correlation with urinalysis
**WORK EXPERIENCE**
Project Associate
CSIR-Institute of Microbial Technology (IMTech)
09/2023 – 10/2024
Chandigarh
Tasks:
– Investigated protein-protein interactions of small G-proteins using advanced biochemical assays.
– Performed protein purification, Western blotting, co-immunoprecipitation, pulldown assays, yeast two-hybrid assays, and immunostaining for confocal microscopy.
– Maintained and sub-cultured mammalian cell lines (HeLa, HEK293T) for experimental studies.
– Contributed to research on intracellular signaling mechanisms relevant to lysosomal secretion and autophagy.
**CONFERENCES**
– International e-Conference on frontiers in Industrial Biotechnology (ICFIBT-2020)
– Next Generation Biomaterials for Drug Discovery / 2020
– Advanced Training on Microbial Technology /2021
– Clinical aspects of Endocrinology in Ayurveda /2019
**ADVANCED COURSES**
Drug Hunting: The Science of Making New Medicines – Specialization (Davidson College & Novartis)
– Introduction to Drug Hunting, Target, Assays, and Screening
– Pharmacokinetics, Preclinical Safety, Lead Selection and Optimization, Pre-formulation
**LANGUAGES**
– English: Full Professional Proficiency
– Hindi: Native or Bilingual Proficiency
**Skills:**
– Protein Biochemistry
– Cell Culture & Imaging
– Lab Management
– Protein purification
– Co-immunoprecipitation
– Pathogen identification
– Antibiotic resistance profiling
– Confocal Microscopy
– Plasmid isolation
“`
Cover Letter:
Dear Hiring Manager,
I am writing to express my keen interest in the Molecular Biology Scientist position at D-NOME Biosciences. With a Master’s degree in Medical Biotechnology and hands-on experience in molecular biology and protein biochemistry, I am enthusiastic about the opportunity to contribute to your innovative research endeavors.
During my tenure as a Project Associate at CSIR–Institute of Microbial Technology (IMTech), I was involved in projects focusing on protein–protein interactions of small G-proteins, which are pivotal in cellular signaling pathways. My responsibilities included:
– Protein Purification and Analysis: Executed protocols for purifying proteins and assessing their interactions using techniques like Western blotting and co-immunoprecipitation.
– Molecular Cloning: Designed and constructed plasmids for gene expression studies, facilitating the investigation of protein functions.
– Cell Culture: Maintained and manipulated mammalian cell lines (HeLa and HEK293T) for transfection and expression studies.
– Microscopy: Utilized confocal microscopy to visualize cellular processes and protein localization.
These experiences have honed my technical skills and deepened my understanding of molecular mechanisms, aligning well with the requirements of the Molecular Biology Scientist role at your esteemed organization.
What particularly draws me to D-NOME Biosciences is your commitment to advancing molecular diagnostics and therapeutic solutions. I am eager to apply my expertise to contribute to your ongoing projects and collaborate with a team dedicated to scientific excellence.
I would welcome the opportunity to discuss how my background and skills can benefit D-NOME Biosciences. Thank you for considering my application.
Sincerely,
Medha Gupta
Leave a Reply