Udaykanth Suryavanshi – Unlocking the Secrets of Vitamin B12 for Neurodegeneration Breakthroughs

Introduction:

Udaykanth Suryavanshi is a dedicated biochemist currently pursuing a Ph.D. in Biochemistry at the National Institute of Nutrition in Hyderabad, India. With a strong background in biotechnology and bioinformatics, Udaykanth has conducted cutting-edge research focused on the impact of vitamin B12 supplementation on neurodegeneration in rodent models of diabetes. His expertise lies in molecular biology, animal experimentation, and bioinformatics.

Education:

Ph.D. in Biochemistry (Sep 2019 – Pursuing)

Department of Biochemistry, National Institute of Nutrition, Tarnaka, Hyderabad, India
Thesis: “Impact of Vitamin B12 Supplementation on Neurodegeneration in Rodent Models of Diabetes”

M.Sc. in Biotechnology (July 2016 – May 2018)

Department of Biotechnology, University College of Science Saifabad, Telangana India
Thesis: “Role of a Functional -735 C>T Polymorphism in the promoter region of the MMP-2 gene in breast cancer”

PG Diploma in Bioinformatics (September 2015 – June 2016)

Osmania University, Telangana, India
Thesis: “3D-QSAR and Molecular Docking study of Mycobacterium Tuberculosis H37RV inhibitors by CoMFA and CoMSIA methods”

B.Sc. in Biochemistry (July 2012 – May 2015)

Osmania University, Telangana, India

Skills:

Animal Experimentation, Rodent Behavioral Studies, Cell Culture, Molecular Biology, Histology, Microscopy, Biochemical Techniques, Bioinformatics, Software Handling

Publications:

• Vitamin B12 Modulates D-Galactose-Induced Renal Dysfunction
• Vitamin B12 supplementation attenuates endoplasmic reticulum stress and neuronal cell death in the cerebral cortex of high-fat high-sucrose-fed male mice
• Neuroprotective role of vitamin B12 in streptozotocin-induced type-1 diabetic rat
• Amelioration of D-Galactose induced Renal Injury by Functional Food Mix through AGE/RAGE/NF-κB Dependent Mechanism in a Rat Model
• Effect of Sorbitol on Alpha-Crystallin Structure and Function
• In silico Modelling and Docking Studies of Camptothecin Derivatives

Talks and Presentations:

• Vitamin B12 supplementation attenuates endoplasmic reticulum stress and neuronal cell death induced by high-fat, high-sucrose diet
• Impact of vitamin B12 supplementation on streptozotocin-induced diabetic rat brain
• Role of MMP2 -735 C
• Emerging trends in mutation detection for screening of genetic disorders

Scholarships and Awards:

• DBT travel grant to attend International Conference: 22nd IUNS-ICN in Tokyo, Japan (2022)
• Qualified Telangana State-State eligibility test for lectureship TS-SET Lectureship (2019)
• Indian Council of Medical Research – Junior Research Fellowship award in Life Science Category (2018)
• Received Certificate of Appreciation as a valued Evaluator for National Camp Examination of Vidyarthi Vigyan Manthan (2019)

Workshops and Conferences Attended:

• Ad-hoc training course on “Care, Breeding, Management, Experimentation techniques and Ethical treatment of laboratory animals”
• Participated in the workshop on “Research Methodology and Skills Sets”
• Value added course on “Python programming language”
• Attended a workshop on “Purification and Biochemical Characterization of Recombinant Protein”
• Workshop on Basic of Bioinformatics
• Attended workshop on “BMC formation and PBR preparation for conservation of Biodiversity in Telangana State”
• Work carried out and presented a complete thesis on “Screening and Diagnosis of Thalassemia”
• Attended Workshop on “Radio Chemistry and Applications of Radio Isotopes”
• Participated in an International Congress of Cell Biology
• Participated in the Nano3Bio dissemination event entitled “The Future of Chitosans”

References:

Dr. G Bhanuprakash Reddy, Scientist ‘G’, Head, Dept. of Biochemistry, National Institute of Nutrition, Tarnaka, Hyderabad, India

Dr. V Sudhakar Reddy, Scientist ‘C’, Dept. of Biochemistry, National Institute of Nutrition, Tarnaka, Hyderabad, India

Dr. R Tamizhselvi, Professor Grade I, Dept. of Biotechnology, Vellore Campus, Vellore

“`

Cover Letter:

I am S. Udaykanth, submitted my Ph.D. thesis to Osmania University, Hyderabad in the field of Biochemistry. Over the course of my academic journey, I have gained substantial hands-on exprience in various molecular biology techniques involving RNA, DNA and protein analysis.
During my masters degree (Biotechnology) I worked with human blood samples, successfully extracting DNA and performing restriction enzyme digestion to identify the genotypes associated with breast cancer pathogenesis.
In my Ph.D work I have performed protein quantification, western blotting, RT-PCR, and ELISA techniques. I have exprience in gel filtration chromatograpghy required for protein seperation and isolation from eye lens. I have strong basis in data analysis using graphpad prism.
With my strong technical skills and laboratory experience, I beleive that I can significantly contribute in the advertised project. Please find my CV attached for ypur kind conideration. I hope to hear a positive reponse.
Thank You

Udaykanth