Gauri Srivastava – Unveiling the Secrets of Microbial Biotransformation that Could Change Medicine Forever

Gauri Srivastava, Ph.D.

Ph.D. in Biotechnology

Summary:

A passionate researcher with three years of experience as a senior research fellow in microbiology and biotechnology. Expert in microbial biotransformation, fermentation, antimicrobial assays, and microbial cell immobilization. Skilled in analytical techniques such as thin-layer chromatography, spectrophotometry, CAM assay (angiogenesis), centrifugation, LC-MS analysis, and scientific writing. Eager to contribute knowledge and skills to impactful research in the field.

Professional Experience

Senior Research Fellow at Amity University, Noida (CSIR Funded Project)

July 2018 – June 2021

Patents

1. A method for providing biotransformation of vinblastine into vincristine using an endophyte Fusarium equiseti. Prov. No.- [Phone Hidden].
2. A method for rapid bioconversion of vinblastine to vincristine using Pseudomonas fluorescens MTCC2421. Prov. No. – [Phone Hidden].
3. Isolated and identified Fusarium equiseti nucleotide sequence submitted to NCBI Gene Bank with an Accession No.- SUB14393723 FUSARIUM PP709003.

Education

Doctor of Philosophy (Ph.D.) in Biotechnology
Amity University, Noida
July 2020 – June 2025
Thesis Title: Microbial biotransformation of pharmaceutically important indole alkaloids

Master of Technology (M. Tech) in Biotechnology (Industrial Microbiology)
SHUATS, Agriculture University, Allahabad
2014 – 2016

Dissertation: Characterization and antibacterial activity of partially purified exopolysaccharide produced from Lactobacillus plantarum against foodborne pathogens.

Bachelor of Technology (B. Tech) in Biotechnology (Industrial Microbiology)
SHUATS, Agriculture University, Allahabad
2010 – 2014

Dissertation: Quality monitoring of treated sewage water used for irrigation purpose in Allahabad.

Research Experience

Doctor of Philosophy (Ph.D.) in Biotechnology
Amity University, Noida
July 2020 – June 2025
Thesis Title: Microbial biotransformation of pharmaceutically important indole alkaloids

• Thesis work comprised a microbial biotransformation system developed to transform vinblastine (VBL) and ajmalicine (AJM) into vincristine (VCR) and serpentine (SEP) using endophyte Fusarium equiseti and two bacterial strains Pseudomonas aeruginosa 8485 and Pseudomonas fluorescens 2421.
• Validated anticancer potential of VCR through CAM assay, a widely used model for angiogenesis studies.

Research Publications

1. Srivastava G, Mittal R, Srivastava N, Ganjewala D. Exploring the potential of two Pseudomonas species to produce vincristine from vinblastine via biotransformation. Scientific Reports. 2024 Aug 23;14(1):19652.
2. Srivastava G, Mittal R, Srivastava N, Srivastava S, Ganjewala D. Biotransformation of vinblastine into vincristine using a fungal endophyte Fusarium equiseti along with the assessment of its antiangiogenic properties. Zeitschrift für Naturforschung C. 2025.
3. Srivastava G, Mukherjee E, Mittal R, Ganjewala D. Geraniol and citral: recent developments in their anticancer credentials opening new vistas in complementary cancer therapy. Zeitschrift für Naturforschung C. 2024 Apr 19(0).
4. Srivastava G, Ganjewala D. An update on the emerging neuroprotective potential of Moringa oleifera and its prospects in complimentary neurotherapy. Phytomedicine Plus. 2024 Feb 11:100532.
5. Mittal R, Srivastava G, Ganjewala D. Screening of Microorganisms Capable of Biotransforming Certain Monoterpenes Using Substrate Toxicity Test. Journal of Pure & Applied Microbiology. 2024 Mar 1;18(1).
6. Ganjewala D, Bansal H, Mittal R, Srivastava G. Unraveling of inhibitory potential of phytochemicals against SARS-COV-2 using in-silico approach. In Herbal Medicines 2022 Jan 1 (pp. 471-500). Academic Press.
7. Mittal R, Srivastava G, Ganjewala D. An update on the progress of microbial biotransformation of commercial monoterpenes (vol 77, 225, 2021). Zeitschrift fur Naturforschung Section CA Journal of Biosciences. 2022 Jul 26;77(7-8):363.
8. Bansal H, Pravallika VS, Srivastava G, Ganjewala D. Bioactivity assessment of essential oils of Cymbopogon species using a network pharmacology approach. Biologia futura. 2022 Mar;73(1):107-18.

Conferences and Workshops

• International conference on “Biotechnological Interventions for Health, Agriculture and Circular Economy” – MNNIT, Allahabad (Feb 23-25, 2024).
• International conference on “Advances in Cancer Biology, Prevention and Therapy” – SRMU, Lucknow (May 24-25, 2022).

Professional Skills:

Microbial biotransformation, Fermentation, Antimicrobial assays, Thin-layer chromatography, LC-MS analysis, Spectrophotometry, Centrifugation, CAM assay (angiogenesis), Microbial cell immobilization, Leadership, Time management, Teamwork, Focus and dedicated, Adaptability, Scientific writing

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Cover Letter:

**Dr. Gauri Srivastava**
ORCID: 0000-0002-8482-4917
19 June 2025
**Hiring Manager**
Kwality Pharmaceuticals Ltd.
Subject: Application for the Position of Microbiology Quality Executive
Dear Hiring Manager,
I am writing to apply for the position of _Microbiology Quality Executive_ at Kwality Pharmaceuticals. I hold a Ph.D. in Biotechnology and bring over three years of dedicated research experience as a Senior Research Fellow in a CSIR-funded project focused on microbial biotransformation and quality-related microbial studies.
During my tenure at Amity University, I developed expertise in fermentation, microbial cell handling, antimicrobial assays, and quality control techniques, alongside analytical tools such as TLC, spectrophotometry, and LC-MS. I have worked rigorously in maintaining sterile laboratory environments and precise documentation of microbiological processes, which are critical to pharmaceutical quality assurance.
I am enthusiastic about contributing to Kwality Pharmaceuticals’ legacy of high-quality and compliant product manufacturing. With my scientific background, strong attention to detail, and commitment to quality, I am confident in my ability to support and enhance your microbiology quality team.
Thank you for considering my application. I have attached my resume for your review, and I look forward to the opportunity to contribute to your organization.
Sincerely,
**Dr. Gauri Srivastava**