Umamaheswari S – From Consulting to CRISPR: The Unbelievable Journey of a Passionate Biotechnologist!

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**UMAMAHESWARI S**
Biotechnologist

**Summary:**
Enthusiastic and passionate biotechnologist with a strong desire to learn about emerging trends and techniques in the field. Highly adaptable to diverse working conditions, meticulous in documenting observations with a focus on accuracy, and maintaining a sterile and organized work environment.

**Location:** Bangalore, Karnataka

**Education:**
[hidden] Industrial Biotechnology [81%]— Vivekanandha College of Engg for Women, Tiruchengode. Anna University, Chennai, Tamil Nadu, 2003 – 2007
– HSC [[hidden]]— Holy Angels’ Matriculation School, State Board Salem, Tamil Nadu, 2001 – 2003
– SSLC [[hidden]]— Sri Vidya Mandir Hr. Sec. School, Salem, Tamil Nadu, CBSE Delhi, 2000 – 2001

**Internship Experience:**
**BioTecNika – Bioinformatics Internship**
July 2024 – Present
– Currently working on the project Designing Novel Therapeutic Strategies for Rare Diseases Using CRISPR-Based Functional Genomics.
– Analyzing large-scale genetic datasets to design sgRNAs targeting specific genes associated with rare diseases.
– Developing Python-based computational pipelines for streamline sgRNA selection and validation.
– Gaining expertise in CRISPR technology, bioinformatics tools, and genomic data analysis.
– Strengthening problem-solving, documentation, and teamwork skills through collaborative research.

**Skills:**
– **Bioinformatics Tools:** CRISPR design, sgRNA selection, genomic data analysis
– **Programming & Data Analysis:** Python, R, SQL, Tableau
– **Genomic Research:** Functional genomics, NGS Analysis
– **Molecular Biology Techniques:** PCR, Gel Electrophoresis, Western blotting.
– **Professional Strengths:** Decision-making, problem-solving, teamwork, fast learning, attention to detail

**Work Experience (Non Biotech):**
– **Sutherland Global Services, Chennai**
– Customer Support Executive, October 2007 – May 2008
– **Tata Consultancy Services, Chennai**
– Process Associate, June 2008 – November 2008
– **Sutherland Global Services, Chennai**
– Senior Consultant, November 2010 – July 2015

**Professional Enhancements:**
– **NPTEL** [from 2021 till date]
– Experimental Biotechnology
– Human Molecular Genetics
– Cell Culture Technologies
– Interactomics: Basics & Application
– Data Analysis For Biologists
– Bioinformatics: Algorithms and Applications
– **COURSERA** – Aug 2022- Jan 2023
– Google Data Analytics Professional Certificate
– **Biotecnika Training Program**
– AI ML in Biology, Bioinformatics & Computational Biology (30 Days)

**Project:**
Demonstration of Novel method of Biosynthesis of Nanoparticles employing cash crops of Monocotyledons.

**Planned Career Break:**
Started career in 2007 and progressed from Process Associate to Senior Consultant (Tier II) in Sutherland Global Services in 2015. Took a maternity break in 2015, willing to join back with an organization of repute.
– Took intentional pause to focus on full-time caregiving; Excited and energized to return to work.
– Proactively pursued certifications through remote learning in NPTEL and COURSERA

**Keywords:**
Bioinformatics, CRISPR design, Python, Molecular Biology, Genomic Research, Problem-solving, Data Analysis, Teamwork, PCR, Gel Electrophoresis, Western blotting.

Cover Letter:

**Subject: Application for Genome Analyst Position**
**Respected Hiring Manager,**
**I am excited to apply for the Genome Analyst position at Medgenome. With a strong foundation in bioinformatics, functional genomics, and CRISPR-based research, I am eager to contribute my expertise to your team. My recent experience as a Bioinformatics Intern at BioTecNika has allowed me to apply computational tools and data analysis techniques to real-world genomic challenges, making me a strong candidate for this role.**
**I am excited about this opportunity to work on cutting-edge genomic research that can drive meaningful advancements in healthcare. My analytical mindset, problem-solving abilities, and ability to collaborate effectively with interdisciplinary teams make me confident in my ability to thrive in this role.**
**I would welcome the opportunity to discuss how my experience and skills align with your needs. Thank you for your time and consideration. I look forward to hearing from you.**
**Sincerely,**
**Umamaheswari S**

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