Prafulla Srivastava – Unlocking the Secrets of Biotechnology: Meet the Rising Star Revolutionizing Drug Discovery!

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**Summary**

**Name:** Prafulla Srivastava
**Location:** Ayodhya, Uttar Pradesh
**Gender:** Male
**Nationality:** Indian
**Profile**
Dynamic and passionate biotechnologist with a strong foundation in both wet and dry lab practices. Proficient in handling advanced laboratory instruments and techniques, including SDS-PAGE, chromatography, plant tissue culture, and in silico gene characterization. Actively participated in esteemed national and international conferences, showcasing research aptitude and networking with global experts. Completed comprehensive training programs in biotechnology, enhancing technical and analytical skills. A well-rounded individual with leadership experience in cultural events, demonstrating exceptional teamwork and organizational abilities. Driven to excel in innovative biotechnological research and contribute to groundbreaking advancements.

**Professional Experience**

**Research Associate/Project Lead**
**Biotecnika Info Labs Pvt Ltd**
*2024/06 – 2025/05*
– Designed and implemented a data-driven workflow integrating machine learning models and bioinformatics tools for drug discovery.
– Curated and pre-processed datasets of natural compounds, including their physicochemical properties, ADME profiles, and bioactivity data.
– Extracted molecular descriptors using cheminformatics tools like RDKit and SwissADME.
– Developed and validated predictive machine learning models to evaluate compound efficacy and drug-likeness.
– Conducted statistical analysis and visualization of data using Python.

**Trainee**
**Experiome Biotech Private Limited**
*2022/06 – 2022/07*
– Completed training in biotechnology, acquiring expertise in wet lab techniques and proficient in dry lab practices.
– Skilled in laboratory protocols, data analysis, and molecular biology research methodologies.

**Trainee**
**Biogrademy**
*2024/08 – 2025/03*
Leaning basics of python and bio python libraries

**Trainee**
**CytoGene Research & Development LLP**
*2022/02*
– Training of basic bioinstrumentation tools.

**Student Coordinator**
**Apni Pathshala, SRMU**
*2025/01 – 2025/06*
Part of CSR initiative for primary studies of students in surrounding villages.

**Project Dissertation**
**National Centre for Cell Science**
– Investigated the role of secretory PD-L1 in modulating T-cell exhaustion and apoptosis.
– Designed and optimized Western blot, pull-down assays, and co-immunoprecipitation.
– Hands-on experience in protein concentration, SDS-PAGE, PVDF transfer, antibody probing, and chemiluminescence detection.
– Performed ELISPOT/activation assays and used Jurkat + co-culture systems to validate secretory PD-L1’s functional role.

**Education**

**M.Sc. Biotechnology**
**Guru Jambheshwar University of Science and Technology**
*2023/07 – Present*
Highly motivated MSc Biotechnology graduate with hands-on experience in advanced laboratory techniques.

**B.Sc. (Hons) Biotechnology**
**Shri Ramswaroop Memorial University**
*2020/08 – 2023/06*

**Skills**
PCR, Chromatography, Gel electrophoresis, HPLC, Protein Purification, Cell Proliferation Assays, Machine learning, Cell cultures, Python, Molecular Cloning, Immunoprecipitation, Scientific Writing

Keywords: PCR, Chromatography, Gel electrophoresis, HPLC, Protein Purification, Cell Proliferation Assays, Machine learning, Cell cultures, Python, Molecular Cloning, Immunoprecipitation, Scientific Writing, English, Hindi

Cover Letter:

Hiring Manager
MedGenome Labs Pvt. Ltd.
Bangalore, India

Subject: Application for the Position of Genome Analyst Trainee

Dear Hiring Manager,

I am writing to express my interest in the position of Genome Analyst Trainee at MedGenome Labs, as advertised. As a postgraduate in Biotechnology with a strong foundation in molecular biology, genomics, and bioinformatics, I am excited by the opportunity to contribute to your innovative work in clinical genomics and next-generation sequencing (NGS).

Currently, I am engaged as a dissertation trainee at the National Centre for Cell Science (NCCS), where I have been involved in projects related to protein biomarker isolation and machine learning-based anti-diabetic drug discovery. This experience has strengthened my skills in molecular biology techniques, data analysis, and scientific problem-solving, making me confident in handling responsibilities such as QC of NGS data, variant analysis, and literature curation.

MedGenome’s commitment to advancing precision medicine in oncology and rare diseases deeply aligns with my passion for translational research. I am particularly drawn to the collaborative and fast-paced environment you foster, and I am eager to contribute to your ongoing efforts while growing under the mentorship of your esteemed team.

I am confident that my technical proficiency, meticulous attention to detail, and proactive mindset make me a strong candidate for this role. I look forward to the opportunity to discuss how my background and interests align with the goals of MedGenome Labs.

Thank you for considering my application.

Sincerely,
Prafulla Srivastava

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