Curriculum Vitae
Summary
Bindumadhuri Cavuturu
[hidden] in Biotechnology with a focus on Drug Discovery. Enthusiastic, hardworking, and sincere individual with a keen interest in establishing a career in life science research.
Work Experience
Research Associate-I, National Institute of Pathology, Delhi
April 2023 – August 2024
– Conducted in-silico screening and MD simulations to identify potential inhibitors against specific kinesins
– Participated in MTT assays to test inhibitory activity on cancer cells
Junior Research Analyst, Excelra Knowledge Private Solutions, Hyderabad, India
March 2021 – March 2023
Education
- [hidden] (Biotechnology-Drug discovery), Pondicherry University
2012 – 2021 - [hidden] (Biomedical Genetics), Vellore Institute of Technology
2009 – 2011 - Bachelor Degree, Venkata Giri Rajas (VRIAS)
2006 – 2009 - Intermediate, Sree Chaitanya College, Nellore
2003 – 2005 - Secondary, Sullurpeta
2002 – 2003
Achievements
- Oral presentation at the 36th Annual Conference of Indian Association of Biomedical Scientists
- Training in Animal Cell Culture Techniques by NCCS, Pune
- Participation in various national and international conferences
Publications
- Bindu Madhuri Cavuturu, et al., Molecular dynamics of interaction of Sesamin and related compounds with the cancer marker β-catenin, Journal of Biomolecular Structure and Dynamics, 2019
- Muddasarul Hoda, et al., Stabilizers influence drug–polymer interactions and physicochemical properties of disulfiram-loaded poly-lactide-co-glycolide nanoparticles, Future Science OA, 2017
Skills
Cell Culture, Western Blot, PCR, Human DNA Isolation, Docking, Molecular Dynamic Simulation Studies, Basic Microbial Technologies, Postgraduate Level Skills in Karyotyping
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Cover Letter:
My name is Bindumadhuri Cavuturu, a [hidden] graduate in Biotechnology in drug discover discipline from Pondicherry University with Prof. N. Arumugam in 2021. The main motif of my doctoral study was to identify the anticancer potential of sesamin and their analogues against the prime marker for colorectal cancer β-catenin. β-catenin has attracted my attention to consider it for my study because of its significant contribution in the occurrence of 80 % of sporadic colorectal cancers. In the normal cells, β-catenin is involved in several cellular and nuclear acts that were allied in the cell development and division. In my thesis, I have used rigid docking and MD simulation studies in order to identify the best probable inhibitors among the sesamin and its analogues. Further the identified inhibitors were tested on the SW480, HT29 cell lines for their antiproliferative activity by MTT assay, flowcytometry and western blott studies and it was found that sesamin, sesamolin were having the potency to reduce the total β-catenin levels. After my doctoral studies during COVID times I worked as Junior Research analyst in Excelra Knowledge Private solutions which is a work from home opportunity from March 2021 to April 2024. Later I got a Post doctoral fellow opportunity in an ICMR institute ‘National Institute of Pathology’, Delhi under Dr. [hidden] Raju Bagadi from 24 April 2023 to 31 August 2024. During all part of my educational and professional experiences I am having expertise in animal cell culture (handling the cell lines SW480, HT-29, HEK293, MDA-MB-231, and A549), Western Blotting, Flow Cytometry, Virtual screening by Schrodinger, MD simulations using Gromacs and Schrodinger. During this period, I have got credit for one first author publication (Cavuturu et al.,2018), 2 publications as a co-author and two more manuscripts are ready to submit. Between these 2 more publications that to be submitted one manuscript consist of my wet lab experiences. Currently I am looking for a suitable job opportunity to have an extended career. With this brief introduction I am writing to you to choose my profile for a suitable vacancy if you have any. Thanking you Sincerely, [hidden]
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